Motif ID: RXRA_VDR{dimer}.p2

Z-value: 0.969


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VDRchr12_-_46585032-0.097.5e-01Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_48966394 2.162 TRABD
TraB domain containing
chr22_+_48966480 1.870 NM_025204
TRABD
TraB domain containing
chr19_-_14121728 1.173 LPHN1
latrophilin 1
chr7_+_44762311 1.148 NM_174929
ZMIZ2
zinc finger, MIZ-type containing 2
chr13_+_113369470 1.112 NM_002929
GRK1
G protein-coupled receptor kinase 1
chr21_-_46399900 1.003 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr11_+_72765318 0.997 NM_032871
RELT
RELT tumor necrosis factor receptor
chr1_-_1840564 0.974 NM_178545
TMEM52
transmembrane protein 52
chr9_-_34554800 0.925 CNTFR
ciliary neurotrophic factor receptor
chr1_+_93830169 0.839 LOC100129046
hypothetical LOC100129046
chr11_-_780103 0.816 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr1_+_93830106 0.805 LOC100129046
hypothetical LOC100129046
chr7_+_154720416 0.764 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr11_+_63883192 0.756 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr7_+_154720547 0.674 INSIG1
insulin induced gene 1
chr19_-_1601246 0.634 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr16_-_31135895 0.634 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr11_+_76561471 0.593 MYO7A
myosin VIIA
chr17_-_31831093 0.589 NM_001123392
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
TBC1 domain family, member 3F
chr1_-_226530350 0.581


chrX_+_153339814 0.577 NM_017514
PLXNA3
plexin A3
chr16_+_28797309 0.561 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr7_+_128365226 0.558 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr19_+_60878238 0.556 NM_001130072
NM_013333
EPN1

epsin 1

chr12_+_55896844 0.553 NM_007224
NXPH4
neurexophilin 4
chr19_+_60878381 0.545 EPN1
epsin 1
chr1_-_20122638 0.534 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr12_+_131577229 0.532 NM_001142641
FBRSL1
fibrosin-like 1
chr9_+_130838720 0.531 FAM73B
family with sequence similarity 73, member B
chr22_+_16973556 0.527 TUBA8
tubulin, alpha 8
chr17_+_4434024 0.527 NM_198501
SMTNL2
smoothelin-like 2
chr10_-_50269912 0.519 NM_001080520
DRGX
dorsal root ganglia homeobox
chr14_-_100104014 0.517 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr10_+_35524835 0.512 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr1_-_199348316 0.503 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr11_+_2378559 0.492 TSSC4
tumor suppressing subtransferable candidate 4
chr22_+_16973399 0.490 NM_001193414
NM_018943
TUBA8

tubulin, alpha 8

chr19_+_60878392 0.478 EPN1
epsin 1
chr19_+_47509274 0.471 NM_173633
TMEM145
transmembrane protein 145
chr11_-_64283945 0.461 PYGM
phosphorylase, glycogen, muscle
chr1_-_153209625 0.461 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr11_-_66945190 0.460 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr17_+_2646481 0.458 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr8_+_10420465 0.443 NM_001197020
NM_198464
PRSS55

protease, serine, 55

chr17_-_70367479 0.440 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr1_-_3806683 0.431 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr9_+_139245029 0.427 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr19_-_51889002 0.426 PRKD2
protein kinase D2
chr19_+_13111072 0.404 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr19_-_41090960 0.403 TYROBP
TYRO protein tyrosine kinase binding protein
chr7_+_97679501 0.393 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr8_-_139995417 0.392 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr17_-_31528027 0.392 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr19_+_1892157 0.389 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr2_+_111206620 0.382 NM_001142807
ACOXL
acyl-CoA oxidase-like
chr12_+_56284867 0.376 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr1_+_35031185 0.375 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr19_-_63550712 0.373 A1BG
alpha-1-B glycoprotein
chr19_-_52679287 0.371 NM_007059
KPTN
kaptin (actin binding protein)
chr1_-_3806564 0.362 C1orf174
chromosome 1 open reading frame 174
chr1_+_224803226 0.361 C1orf95
chromosome 1 open reading frame 95
chr4_+_1872150 0.355 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr11_+_1170045 0.354 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr5_-_178984192 0.352 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_-_203592538 0.352 NM_018203
KLHDC8A
kelch domain containing 8A
chr19_-_51010272 0.340 NM_030785
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr16_+_31027231 0.335 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_-_48700824 0.331 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr19_+_60878422 0.329 EPN1
epsin 1
chr1_-_33110668 0.327 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr2_+_74594093 0.323 TLX2
T-cell leukemia homeobox 2
chr3_+_185515108 0.314 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_128312922 0.311 NM_001195194
TP53AIP1
tumor protein p53 regulated apoptosis inducing protein 1
chr10_+_11087259 0.311 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr7_+_128365482 0.310 NM_032643
IRF5
interferon regulatory factor 5
chr21_+_44699796 0.310 NM_030891
LRRC3
leucine rich repeat containing 3
chr17_+_18320822 0.310 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr1_+_173303616 0.304 NM_022093
TNN
tenascin N
chr1_+_19807168 0.301


chr6_+_31910623 0.301 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr16_-_88295595 0.296 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr15_-_38420414 0.295 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr11_+_76516957 0.292 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr3_+_185514937 0.291 NM_001194946
NM_001194947
NM_198241
NM_198242
NM_198244
EIF4G1




eukaryotic translation initiation factor 4 gamma, 1




chr18_-_57711283 0.290 NM_173557
RNF152
ring finger protein 152
chr17_+_4434582 0.285 NM_001114974
SMTNL2
smoothelin-like 2
chr9_+_138367329 0.285 NM_001145639
GPSM1
G-protein signaling modulator 1
chrX_-_109570113 0.285 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chrX_-_48661226 0.284 NM_006875
PIM2
pim-2 oncogene
chr1_+_224803123 0.280 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr16_-_2201011 0.276 NM_182563
C16orf79
chromosome 16 open reading frame 79
chr6_+_31538934 0.271 NM_006674
HCP5
HLA complex P5
chr9_+_34448810 0.271 NM_012144
DNAI1
dynein, axonemal, intermediate chain 1
chr19_+_44591589 0.271


chr19_+_10652025 0.271


chr19_+_1334877 0.270 NM_024407
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr19_-_52679222 0.269 KPTN
kaptin (actin binding protein)
chr16_-_65742323 0.263 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr8_+_22493928 0.260 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr17_+_35751796 0.258 NM_001024809
RARA
retinoic acid receptor, alpha
chr17_-_31616071 0.257 NM_001001418
NM_032258
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr19_-_41091023 0.254 TYROBP
TYRO protein tyrosine kinase binding protein
chr16_+_31027115 0.254 NM_001122957
NM_005881
BCKDK

branched chain ketoacid dehydrogenase kinase

chr1_+_44171578 0.254 NM_001136215
NM_057090
NM_057091
ARTN


artemin


chr4_-_2727548 0.248 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr19_-_3820012 0.246 NM_001145640
NM_015174
ZFR2

zinc finger RNA binding protein 2

chr2_+_104837004 0.238


chr21_+_44169706 0.236 NM_001037553
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_113038202 0.235 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr16_+_620932 0.231 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr16_+_28211123 0.227 NM_001024401
SBK1
SH3-binding domain kinase 1
chr11_-_780065 0.226 CEND1
cell cycle exit and neuronal differentiation 1
chr9_-_139027435 0.226 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_+_1334904 0.223 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr19_+_63670449 0.221 ZNF324
zinc finger protein 324
chr19_+_1334898 0.220 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr9_+_133259330 0.220 PRRC2B
proline-rich coiled-coil 2B
chr1_+_207823667 0.219 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr9_+_130684601 0.215 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr17_-_74990157 0.213 NM_001082575
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr22_+_48740432 0.212 PIM3
pim-3 oncogene
chr3_+_185515013 0.209 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr3_-_49117169 0.208 NM_005051
QARS
glutaminyl-tRNA synthetase
chr3_+_49183983 0.208 NM_173546
KLHDC8B
kelch domain containing 8B
chr11_+_124115051 0.207 NRGN
neurogranin (protein kinase C substrate, RC3)
chr12_-_6668085 0.204 NM_001039916
ZNF384
zinc finger protein 384
chr7_+_100515439 0.203 NM_030961
TRIM56
tripartite motif containing 56
chr8_+_38877909 0.202 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr17_+_77603064 0.199 GPS1
G protein pathway suppressor 1
chr10_+_80569464 0.197 ZMIZ1
zinc finger, MIZ-type containing 1
chr19_-_41091045 0.196 NM_001173514
NM_001173515
NM_003332
NM_198125
TYROBP



TYRO protein tyrosine kinase binding protein



chr8_-_23596346 0.195 NM_006167
NKX3-1
NK3 homeobox 1
chr17_-_36475652 0.193 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr1_-_23623713 0.191 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr16_+_31027249 0.189 BCKDK
branched chain ketoacid dehydrogenase kinase
chr10_-_30356344 0.189 KIAA1462
KIAA1462
chr7_+_143331954 0.188 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr3_-_13032130 0.182


chr19_-_54212158 0.180 NM_000894
LHB
luteinizing hormone beta polypeptide
chr21_+_45649429 0.176 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr22_+_29819343 0.176 SMTN
smoothelin
chr19_+_13122272 0.175 NM_004907
IER2
immediate early response 2
chr9_+_129605275 0.174 NM_001018078
FPGS
folylpolyglutamate synthase
chr1_+_2149993 0.173 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr1_-_199608941 0.172 TNNT2
troponin T type 2 (cardiac)
chr16_+_658081 0.172 NM_138769
RHOT2
ras homolog gene family, member T2
chr8_-_142307854 0.172 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr16_-_28210867 0.170


chr9_+_135213235 0.170 NM_017503
SURF2
surfeit 2
chr1_-_153491761 0.169 NM_006589
NM_198264
FAM189B

family with sequence similarity 189, member B

chr16_+_31027255 0.168 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_+_45996881 0.166 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr19_-_18868395 0.166 LASS1
LAG1 homolog, ceramide synthase 1
chr19_-_54267932 0.163 NM_031886
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr14_+_69021149 0.163 NM_001161498
UPF0639
UPF0639 protein
chr7_-_126679540 0.162 NM_001127323
GRM8
glutamate receptor, metabotropic 8
chr16_+_55950195 0.162 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr4_-_2727816 0.162 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr11_+_359723 0.161 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr4_+_2764510 0.161 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr1_+_149309703 0.160 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr1_-_151852128 0.160 NM_080388
S100A16
S100 calcium binding protein A16
chr12_+_54700955 0.159 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr13_+_23742846 0.158 SPATA13
spermatogenesis associated 13
chr1_-_39929654 0.158 NM_016257
HPCAL4
hippocalcin like 4
chr6_+_30960305 0.156 NM_013993
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_+_44628080 0.155 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr16_+_2195424 0.155 NM_022372
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr17_+_7125702 0.154 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr5_-_32210084 0.153 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr19_+_54962075 0.152 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr15_-_87565813 0.150 NM_000326
RLBP1
retinaldehyde binding protein 1
chr10_-_103525646 0.149 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr19_+_46951237 0.148 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr17_+_7846636 0.148 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr17_-_39333490 0.147 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr7_+_156491223 0.147 MNX1
motor neuron and pancreas homeobox 1
chr17_+_77528782 0.146 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr5_+_131621230 0.144 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr17_-_71580171 0.144 SRP68
signal recognition particle 68kDa
chr1_+_154816142 0.142 NM_001105669
TTC24
tetratricopeptide repeat domain 24
chr16_+_11978002 0.141 NM_032167
RUNDC2A
RUN domain containing 2A
chr12_-_55920741 0.140 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_201420927 0.140 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr17_-_77640237 0.139


chr17_+_75507750 0.137


chr7_+_75669130 0.135 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr17_+_77528699 0.134 NM_024083
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr17_-_71580177 0.133 SRP68
signal recognition particle 68kDa
chr19_+_44628091 0.133 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr6_-_32253819 0.132 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr1_-_37272295 0.131 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr3_+_51716120 0.131 NM_000839
NM_001130063
GRM2

glutamate receptor, metabotropic 2

chr16_-_4232053 0.129 NM_001098814
SRL
sarcalumenin
chr10_-_43212703 0.129 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr17_+_77603028 0.128 NM_004127
NM_212492
GPS1

G protein pathway suppressor 1

chr16_+_55180767 0.128 NM_005954
MT3
metallothionein 3
chr19_+_44628115 0.128 NM_003169
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr9_+_130839033 0.128 NM_032809
FAM73B
family with sequence similarity 73, member B
chr12_+_56299959 0.127 NM_133489
SLC26A10
solute carrier family 26, member 10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.